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It is well known that the pathogenic mechanism of algic posttraumatic syndrome is still incompletely understood. Although multiple attempts have been made to reduce chronic regional pain syndrome to a single pathophysiologic mechanism (e.g., sympatho-afferent coupling), it has become increasingly accepted that there are multiple mechanisms involved. Only in the past few years, has it been recognized that chronic regional pain syndrome is not simply a sympathetically mediated peripheral pain condition but rather is...