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Background It is still a challenge for physicians and researchers to identify the patients at risk, to make an early diagnosis and to do a correct monitoring for the progress of periodontitis. According to the research literature, Immunoglobulin A (IgA) is the first line of oral mucosal defense against bacterial invasion, including periodontitis. Also, 8-Hidroxy-2-Deoxy Guanosine (8-OHdG) is a result of DNA modification suffered by the attack of free radicals resulted from the oxidative stress processes in periodo...