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Background This paper aims to assess the activity of salivary cotinine in a study group before and after the use of an aqueous solution obtained from Prunus spinosa, and also the evaluation of a possible correlation between its action and levels of salivary cotinine. Methods The study group was made of 50 volunteers: 25 volunteers that used for a week aqueous solution made from dried fruit pulp of the species Prunus spinosa and 25 volunteers who used a blank solution at the same time, evaluating the comparative re...