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SALIVARY 8 – HIDROXY-2-DEOXYGUANOSINE AND URIC ACID AS INDICATORS IN TREATMENT OF CHRONIC PERIODONTITIS
(STEF92 Technology, 2015, Balaban, D.P., Petcu, L.C., Caraiane, A., Grigorian, M., Puscasu, C.G.)
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Background: Periodontal disease is an inflammatory disorder which affects periodontal structures. Oxidative stress is involved in mechanisms of periodontal destruction. 8–hydroxy–2–deoxyguanosine (8–OHdG) is the product of oxidative DNA damage and its levels increase in saliva of patients with periodontal disease. Uric acid (UA) is a major salivary antioxidant and its levels decrease in periodontitis. Objective: This study aims to evaluate the levels of 8–OHdG and UA in saliva and to correlate with CPITN...



