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QUALITY OF LIFE AND FUNCTIONAL STATUS IN PATIENTS WITH PSORIATIC ARTHRITIS
Abstract
Introduction The heterogeneous distribution of clinical manifestations in psoriatic arthritis has a major influence on the quality of life and physical function in these patients. Although impairment of peripheral joints is less severe than in patients with rheumatoid arthritis for an equal duration, the impact on functional and quality of life indices has been similar [1], with predominance of joint pain and socio-emotional disorders in patients with PA. Aim To determine the relationship between functional status and quality of life in patients with psoriatic arthritis Material and methods A group of 88 patients with psoriatic arthritis (PsA) was evaluated for mobility of the peripheral and spinal joint, disease activity, psoriasis severity and quality of life. HAQ-DI, BASFI, BASMI, the number of ankylosing and deformed joints, vertebral mobility indices and PASI score were calculated. Results There has been a decrease in articular mobility since the early stages of the disease, particularly in women (HAQ-DI = 1.22 ± 0.83 in men versus 1.38 ± 0.78 in women, p=NS). Spinal mobility was reduced in men in early stages of the disease (Schober test=3.6 ± 1.74). Functional scores were correlated with the progression of joint disease (HAQ-DI, p=0.03; BASMI, p=0.004; BASFI, p=0.03) and with a poor quality of life as measured by SF-36 (p <0.001). The SF-36 score had a total mean value of 41.2± 19.7 and it is well correlated with the tender joints count (p=0.03), low back pain (p=0.008) and biological disease activity (ESR, CRP), p< 0.05. Conclusion Functional status impairment and disease activity in patients with psoriatic arthritis has a major impact on quality of life, and the SF-36 score appears to be an accurately tool for assessing the quality of life in these patients.
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