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THE STUDY OF BIOLOGICAL ANTIAGING PARAMETERS TO PATIENTS TREATED WITH SAPROPELIC TECHIRGHIOL MUD
Abstract
Aging is one of the most amazing biological processes. There are more than 300 theories that try to explain the phenomenon of aging from biological but also social perspective. The most involved in this process are those that secrete hormones from the ovary (estradiol), from the testis (testosterone), from the adrenal (DHEA, cortisol) and from the pituitary gland (GH - growth hormone). This paper focuses on the study of endocrine changes of pituitary-adrenal axis as an indicator of biological aging under the influence of peloidotherapy. We conducted a prospective clinical trial started in June 2013 and is still ongoing in present, selecting research participants according to inclusion and exclusion criteria established in compliance with the norms of elaboration of a scientific paper. The study group has comprised a total of 22 patients with ages between 51 - 72 years old. Each subject were made hormones determination: IGF-1 performed on admission, at discharge, 1 month and 4 months after discharge and VAS scale (analogous scale for pain). For statistical analysis we used program SPSS 17.0. We obtained the statistically significant results for variation of levels of IGF-1: these increased at the experimental group at discharge and also at 1 month after this point. The levels of pain decreased according to the VAS scale. The data suggest that mud therapy influences the neuroendocrine system. According to the VAS scale, the level of pain decreased, therefore we can say that peloidotherapy improves the quality of life. This study contributes to better understanding of the mechanism of mud treatments for healthy future, and slow and nice aging, in order to follow the principles of evidence based medicine.
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