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The aim of this study is to develop methodology for assessing the economic potential for the clusters development in the regions and to test it in the Central Black Earth Re-gion of Russia. Four problems were solved: 1) it was determined which elements of economic potential are significant for clusters formation in the regions, 2) a system of performance assessment indicators was developed; 3) the economic potential for indus-trial clustering was analyzed in the Central Black Earth Region of Russia; 4) strength, w...