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Introduction: In Europe the prevalence of Parkinson´s disease has been estimated between 65.6 per100 000 inhabitants and 12 500 per100 000 inhabitants. It is one of the most widespread diseases affecting, of course, the patients` quality of life. The aim of our research was to determine the level of quality of life and depression as well as their mutual relationship in patients with Parkinson`s disease, and further to compare the variables monitored with a control group. Method: We adopted the quantitative researc...