Browse

Antibiotics represent one of the most used classes of medications since the discovery of penicillin by Alexander Fleming in 1928. A significant percentage of antibiotics and their metabolites are excreted in the urine, leading to a high concentration in the kidney that may often cause renal impairment. Medication-induced nephrotoxicity represents one of the most common causes of acute kidney injury (AKI) in hospitalized patients. Clinical manifestations are variable, ranging from mild to severe forms, requiring re...

Background: Acute kidney injury (AKI) is an important complication of liver cirrhosis, that increases the mortality in the cirrhotic patients, usually diagnosed as hepatorenal syndrome (HRS). However, there is no proven link between the etiology of liver cirrhosis and the risk of kidney injury. Methods: We conducted a retrospective study on 171 patients with liver cirrhosis admitted to our clinic during a year. We compared data on Child-Pugh and Meld-Na scores, neutrophil-to-lymphocyte ratio (NLR), serum creatinin...